Figure 2

Predicted Epitope Network Residues for all mAbs. The amino-acid composition of the predicted epitope networks is noted as the prefix of the position on top of each array (for example, N160 indicates Asparagine at position 160 of gp120). Residues marked with “E” are predicted to be part of the antibody epitope network. The residues that are highly significantly associated with antibody response (MLR p-value <0.001) are marked by *. Residues reported by Walker et al. to impact PG9 and PG16 sensitivity [4] and those identified by Falkowska et al. for PGV04 [27] are color-coded in blue.