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Table 1 QCMF-significant essential sites in the human EGFR protein, which are nearby either nsSNPs or strictly conserved sites

From: Quantum coupled mutation finder: predicting functionally or structurally important sites in proteins using quantum Jensen-Shannon divergence and CUDA programming

QCMF-significant

Nearby nsSNPs, or strictly

Reference

essential sites

conserved sites

 

N771

773s

[44]

G824

773s

[44]

Y827

829s

[44]

L828

829s

[44]

V834

835c, 836s,860s

[44, 49]

Y891

892s, 895c

[44]

A822

861s

[43, 49, 50]

V844

796c, 798c, 852c

-

A882

884c, 895c, 898c

-

Y900

898c, 901c

-

V902

880c, 901c

-

T909

906c, 936c

-

G911

906c

-

  1. s : non-synonymous snp site, c : strictly conserved site.