From: Improving protein order-disorder classification using charge-hydropathy plots
Method | Sens | Spec | Bal. acc | AUC | F | MCC | PPV | NPV |
---|---|---|---|---|---|---|---|---|
IDP-Hydro | 0.81 ± 0.11 | 0.98 ± 0.02 | 0.90 ± 0.07 | 0.94 ± 0.05 | 0.84 ± 0.08 | 0.82 ± 0.09 | 0.89 ± 0.09 | 0.96 ± 0.02 |
DisProt | 0.77 ± 0.12 | 0.97 ± 0.04 | 0.87 ± 0.08 | 0.94 ± 0.06 | 0.80 ± 0.08 | 0.77 ± 0.10 | 0.85 ± 0.14 | 0.96 ± 0.02 |
TopIDP | 0.76 ± 0.11 | 0.97 ± 0.02 | 0.87 ± 0.07 | 0.93 ± 0.04 | 0.79 ± 0.06 | 0.76 ± 0.06 | 0.84 ± 0.07 | 0.96 ± 0.02 |
FoldUnfold | 0.72 ± 0.12 | 0.97 ± 0.02 | 0.85 ± 0.07 | 0.91 ± 0.07 | 0.77 ± 0.10 | 0.73 ± 0.11 | 0.82 ± 0.11 | 0.95 ± 0.02 |
Guy | 0.70 ± 0.16 | 0.97 ± 0.02 | 0.84 ± 0.09 | 0.90 ± 0.06 | 0.75 ± 0.12 | 0.71 ± 0.13 | 0.82 ± 0.10 | 0.94 ± 0.03 |
B-value | 0.67 ± 0.14 | 0.98 ± 0.02 | 0.83 ± 0.08 | 0.91 ± 0.07 | 0.74 ± 0.11 | 0.71 ± 0.12 | 0.85 ± 0.10 | 0.94 ± 0.02 |
Kyte-Doolittle | 0.61 ± 0.16 | 0.96 ± 0.03 | 0.79 ± 0.09 | 0.87 ± 0.10 | 0.67 ± 0.13 | 0.63 ± 0.14 | 0.78 ± 0.14 | 0.93 ± 0.03 |