Skip to main content

Table 2 The 14 physicochemical properties identified by SVM-BAC.

From: Characterizing informative sequence descriptors and predicting binding affinities of heterodimeric protein complexes

Rank

Aaindex_ID

Description

MED

1

GUYH850105

Apparent partition energies calculated from Chothia index [19]

35.18

2

SNEP660104

Principal component IV [20]

32.71

3

RACS820113

Value of theta (i) (Rackovsky-Scheraga, 1982) [40]

31.48

4

MITS020101

Amphiphilicity index (Mitaku et al., 2002) [41]

31.48

5

MAXF760103

Normalized frequency of zeta R (Maxfield-Scheraga, 1976) [42]

27.77

6

CIDH920104

Normalized hydrophobicity scales for alpha/beta-proteins (Cid et al., 1992) [43]

19.13

7

AURR980119

Normalized positional residue frequency at helix termini C"' (Aurora-Rose, 1998) [44]

17.90

8

TANS770103

Normalized frequency of extended structure (Tanaka-Scheraga, 1977) [45]

16.66

9

CHOP780101

Normalized frequency of beta turn (Chou-Fasman,1978a) [21]

12.96

10

PALJ810107

Normalized frequency of alpha-helix in all-alpha class (Palau et al., 1981) [28]

12.96

11

QIAN880116

Weights for beta-sheet at the window position of -4 (Qian-Sejnowski, 1988) [46]

12.96

12

PALJ810110

Normalized frequency of beta-sheet in all-beta class (Palau et al., 1981) [28]

10.49

13

TAKK010101

Side-chain contribution to protein stability (kJ/mol) (Takano-Yutani, 2001) [47]

9.25

14

Nm-Protein

Average medium-range contacts folding [17]

4.32