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Figure 2 | BMC Bioinformatics

Figure 2

From: NERI: network-medicine based integrative approach for disease gene prioritization by relative importance

Figure 2

Selection of top 5% genes by Δ ' and DADA. The Δ' score selects genes with largest alterations between σ C and σ D , after applying parametric interpolation by power-law. Red and green dots indicate genes with larger coexpression in disease and control, respectively. Gray dots represent genes which are not differentially altered between the two conditions. Blue dots indicate genes obtained by DADA. Genes with large X values participate in many selected shortest paths, which means that they have great importance with regard to the seeds, considering both topological centrality and expression concordance.

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BMC Bioinformatics

ISSN: 1471-2105

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