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Table 4 Independent accuracy measures for AMPS runs on the Master data set at various gap-penalties. Clustering was performed on significance score (from 100 randomisations) with the PAM250 matrix. S c : Scoring method based on STAMP S c [25]. RMSD: Score based on Root Means Squared Deviation. Pfit: Percentage of aligned positions without gap used in fit.

From: OXBench: A benchmark for evaluation of protein multiple sequence alignment accuracy

Gap-penalty

S c

p

RMSD

p

Pfit

0

7.082

<2.2e-16

3.342

<2.2e-16

92.52

3

7.208

2.213e-05

3.176

0.0001652

93.28

6

7.238

0.1558

3.145

NA

93.50

9

7.245

NA

3.156

0.807

93.62

12

7.239

0.01863

3.152

0.7806

93.69

15

7.221

0.0006053

3.151

0.2370

93.77

18

7.192

1.481e-07

3.189

0.02599

93.82

21

7.169

7.09e-ll

3.211

0.002619

93.85

24

7.144

4.038e-15

3.230

0.0001391

93.88

27

7.111

<2.2e-16

3.304

5.281e-07

93.92

30

7.081

<2.2e-16

3.333

1.044e-08

93.95