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Table 5 Results from fitting two-component models to the Barrett data set Maximum likelihood estimates along with selected chromosome arms and corresponding conditional probabilities of harboring a tumor suppressor gene for the two-component models for the Barrett data set.

From: A new mixture model approach to analyzing allelic-loss data using Bayes factors

Model

Arms classified in TSG† group (conditional probability)

2 bb/bin*

0.097

0.708

0.487

0.228

-

5q (1); 9p(0.962); 17p(1)

2 bin

0.073

0.827

-

0.230

-

5q (1); 9p(0.93); 17p(1)

2 bb

0.097

0.708

0.487

0.228

0.000

5q (1); 9p(0.962); 17p(1)

  1. †TSG: tumor suppressor gene
  2. *2 bb; Two-component beta-binomial
  3. 2 bb/bin: Two-component beta-binomial/binomial
  4. 2 bin: Two-component binomial