Figure 4

Deviations of oligonucleotide usage patterns in local loci of two bacterial chromosomes. Lower panel: Distances (eq.8) between n0_4mer patterns calculated for local regions of the leading strand and the standard patterns determined for the clockwise replichor of the two bacterial chromosomes: A) X. fastidiosa 9a5c; B) P. putida KT2440. Local patterns were determined in 15 kbp sliding windows in steps of 7.5 kbp. The 95% confidence interval of distance values is depicted as the turquoise shaded area. The abscissa indicates the coordinates of the chromosomes starting from the putative replication origins (Ori). Positions of the putative chromosomal replication termini are depicted by Term. Upper panel: GC-skew between leading and lagging strands of the (A) X. fastidiosa 9a5c and (B) P. putida KT2440 chromosomes.