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Table 10 Number of inferred periodic genes from real microarray data. Results obtained by using real microarray data are presented here. Permutation tests were used to obtain significance values for the robust spectra. Symbols: N is the length of the time series, M is the number of genes analysed, P (resp. P') is the number of found periodic genes having an unknown frequency (resp. frequency corresponding to the cell cycle length). Notes in the table: aSince the elutriation time course did not show any significant periodic components, we did not perform the test with a fixed frequency. bThe average spectrum showed several major peaks. The one in the vicinity of the assumed cell cycle frequency was chosen manually.

From: Robust detection of periodic time series measured from biological systems

Cell type

Experiment

N

M

P'

P'/M

P

P/M

Source

S.cerevisiae

cdc15

24

5287

981

18.6

946(766)

17.9

[6]

S.cerevisiae

cdc28

17

6103

363

6.0

32(105)

0.5

 

S.cerevisiae

alpha

18

6056

346

5.7

139(468)

2.3

 

S.cerevisiae

elutriation

14

6074

_a

_a

4(193)

0.07

 

Human HeLa

Score3

48

41508

1285b

3.1b

3580(6043)

9.0

[5]

S.pombe

cdc25-1

19

4373

1431

32.7

759

17.4

[7]

S.pombe

cdc25-2

36

4422

2605

58.9

2197

49.7

 

S.pombe

cdc25-sep1

20

4700

2624

55.8

2295

48.8

 

S.pombe

elutriation1

20

4229

1948

46.1

551

13.0

 

S.pombe

elutriation2

20

3961

1453

36.7

384

9.7

 

S.pombe

elutriation3

20

4236

673

15.9

355

8.4

 

S.pombe

elutr.-cdc10-br

22

4647

3131

67.4

2431

52.3

 

S.pombe

elutr.-cdc25-br

21

4272

2405

56.3

767

18.0