Table 5 Detailed statistics on the estimates of p0based on simulations of dependent data. The table displays the mean bias (true – estimated) and standard deviation of estimates for each level of true p0.
From: A comparative review of estimates of the proportion unchanged genes and the false discovery rate
True p 0 | Â | 0.5 | 0.6 | 0.7 | 0.8 | 0.9 | 0.95 | 0.99 |
|---|---|---|---|---|---|---|---|---|
BUM | mean bias | -0.09885 | -0.0744 | -0.0524 | -0.0308 | -0.0525 | -0.0493 | -0.0100 |
| Â | Sd | 0.01555 | 0.0167 | 0.0169 | 0.0194 | 0.0520 | 0.0088 | 0.0010 |
SPLOSH | mean bias | -0.15811 | -0.1179 | -0.0710 | -0.02570 | 0.0180 | 0.0318 | 0.06761 |
| Â | Sd | 0.02702 | 0.0309 | 0.0338 | 0.0398 | 0.0423 | 0.0379 | 0.0560 |
QVALUE | mean bias | -0.15089 | -0.1217 | -0.0895 | -0.0593 | -0.0307 | -0.0142 | 0.0093 |
| Â | Sd | 0.02661 | 0.0306 | 0.0302 | 0.0345 | 0.0368 | 0.0309 | 0.0255 |
Bootstrap LSE | mean bias | -0.18009 | -0.1499 | -0.1080 | -0.0691 | -0.0313 | -0.0126 | 0.0084 |
| Â | Sd | 0.04242 | 0.0382 | 0.0351 | 0.0326 | 0.0299 | 0.0269 | 0.0232 |
SEP | mean bias | -0.15525 | -0.1238 | -0.0915 | -0.0584 | -0.0277 | -0.0134 | 0.0138 |
| Â | Sd | 0.02419 | 0.0239 | 0.0241 | 0.0265 | 0.0269 | 0.0203 | 0.0201 |
LSL | Mean Bias | -0.2710 | -0.2203 | -0.1667 | -0.1110 | -0.0554 | -0.0292 | 0.0017 |
| Â | Sd | 0.13333 | 0.1119 | 0.0902 | 0.0671 | 0.0410 | 0.0221 | 0.0165 |
Mgf | mean bias | -0.18322 | -0.1468 | -0.1349 | -0.0898 | -0.0460 | -0.0235 | 0.0007 |
| Â | Sd | 0.04633 | 0.0401 | 0.0140 | 0.0153 | 0.0160 | 0.0153 | 0.0128 |
PRE | mean bias | 0.14088 | -0.1091 | -0.0770 | -0.0442 | -0.0152 | -0.0021 | 0.0194 |
| Â | Sd | 0.02300 | 0.0239 | 0.0239 | 0.0291 | 0.0310 | 0.0269 | 0.0248 |