Figure 4From: ProfNet, a method to derive profile-profile alignment scoring functions that improves the alignments of distantly related proteinsAverage score for different classes of conserved residues. The classes were clustered by scores from vectors where the conserved residues in the vectors i) were identical, ii) had a positive BLOSUM62 score, iii) had a BLOSUM62 score of zero, and iv) had a negative BLOSUM62 score. The cutoff for the conserved residues are shown on the X-axis and the Z-score is shown on the Y-axis. A residue is considered conserved to a certain degree if it has a value in the profile vector above the cutoff. The solid bold lines are the scores for ProfNet_S, while the dotted lines are the scores for prob_score.Back to article page