Figure 1
From: Statistical distributions of optimal global alignment scores of random protein sequences
Distribution of scores from global alignments of the GS sequence sets of 300aa long. The alignments were carried out with the BLOSUM62 matrix and an affine gap penalty of -7 and -1. The distribution of the scores was fitted with three distribution curves indicated by the solid line. (A) The scores were fitted with the gamma distribution. The fitted parameters are: γ = 44.7296, λ = 0.381642, μ = 158.666, χ2 value is 14.7643 with d.f. = 18; (B) The scores were fitted with the normal distribution. The fitted parameters are: σ = 17.5243, μ = -41.4629; d.f. = 19, χ2 = 729.532; (C) The scores were fitted with the Gumbel distribution. The fitted parameters are: β = 13.66367, μ = -49.3489; d.f. = 19, χ2 = 10563.8.