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Table 1 Alignment accuracies using correct gap costs. Alignment accuracies using a gap open cost of 7 and the optimal gap extension cost of 0.57. P-values are computed using a paired Student's t-test.

From: Ancestral sequence alignment under optimal conditions

Data Set

Measure

Parsimony

Ambiguous Parsimony

ML

Ambiguous ML

Ma et al.

ClustalW

Early Growth

Mean

88.43%

83.83%

87.86%

86.26%

91.74%

91.25%

 

Std.

2.89%

5.94%

2.79%

4.27%

1.69%

2.28%

 

P-value

1.6461 × 10-65

1.1992 × 10-17

N/A

Early Growth Double Length

Mean

64.68%

57.24%

63.54%

59.89%

74.29%

72.35%

 

Std.

5.23%

8.25%

4.99%

7.59%

4.62%

4.30%

 

P-value

1.5922 × 10-103

1.9161 × 10-21

N/A

Late Growth

Mean.

95.76%

96.01%

89.44%

87.52%

96.63%

96.79%

 

Std

1.29%

1.28%

5.44%

7.03%

0.99%

1.10%

 

P-value

7.7818 × 10-10

1.0404 × 10-12

N/A

Late Growth Double Length

Mean

86.71%

88.12%

64.76%

55.67%

89.68%

89.54%

 

Std.

2.71%

2.85%

7.94%

12.62%

2.42%

2.11%

 

P-value

2.1699 × 10-43

2.5033 × 10-50

N/A