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Table 6 Performance indices of FUGUE, PSIBLAST and DP-FUGUE under the single and the MSA query modes. The counts exclude those sequences in the SCOP family in question (that were used to build the MSA). In single query mode we report the average performance. Results are reported using the ROC1-S and the TSS indices. Similar trends were observed with the ROC1-F and the TFF indices.

From: The distance-profile representation and its application to detection of distantly related protein families

Family

Mode

ROC1-S

TSS

  

FUGUE

PSIBLAST

DP-FUGUE

FUGUE

PSIBLAST

DP-FUGUE

a.3.1.1

single

0.4

0.4

2.6

2.8

1.7

3.5

 

MSA

0

2

4

2

3

4

a.3.1.4

single

2.3

1.6

11

6.3

5.3

12.3

 

MSA

1

4

12

4

7

12

a.39.1.5

single

2.8

5

12

7.7

9.5

13.4

 

MSA

15

5

14

16

9

15

b.47.1.4

single

1.6

0

22.3

8.6

1.6

22.3

 

MSA

3

1

23

17

5

23

c.2.1.3

single

0.2

0.1

3.1

7.6

5.4

15.4

 

MSA

2

0

0

14

6

26

c.3.1.2

single

1.8

0.7

9

8.7

5.5

14.1

 

MSA

1

3

12

20

8

19

c.47.1.2

single

4.1

2.3

16.1

8.8

4.8

19.3

 

MSA

12

5

24

19

7

25