Figure 9
From: Harshlight: a "corrective make-up" program for microarray chips
Receiver Operator Curves generated by the AffyComp suite for the SpikeIn133 dataset at 2-fold changes. A. The MAS5 algorithm shows noticeable improvement when Harshlight is used to excise blemishes, both for missing value substitutions as well as for median substitution: approximately 2 extra true positives per chip are discovered. B. The GCRMA algorithm shows a slight improvement of about 0.5 extra true positives per chip under median substitution.