Skip to main content

Table 1 Datasets used for analysis Numbers of nodes and edges in each of the datasets used and a brief description of the methods used to generate the datasets.

From: The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks

Name

Nodes

Edges

Description and Reference

Gavin

1343

3145

Mass screen of yeast protein complexes using affinity purifica tion [15] (Note 1)

Ito

3271

4469

Mass screen of yeast protein interactions using Y2H [18] (Note1)

Lehner

329

406

Y2H interactions between H. sapiens proteins A dataset focused on RNA degradation and other MHCIII functions. [12, 13] (Note 2)

Uetz

1358

1498

Mass screen of yeast protein interactions using Y2H [14] (Note 1).

  1. Notes: 1. The Gavin, Ito and Uetz graphs were all generated from BIND [28] derived datasets, which had GO annotations added and were supplied with v0.9.1 of the 'Osprey' graph visualisation tool [29,30]
  2. 2. The Lehner dataset is a combined set of the data from the two cited papers. These data are available in both IntAct [31] (experiment references EBI-348647, EBI-368082 and EBI-368083) and BIND [28] (refs 130691–130793 and 153087–153089)