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Figure 1 | BMC Bioinformatics

Figure 1

From: An integrated approach of immunogenomics and bioinformatics to identify new Tumor Associated Antigens (TAA) for mammary cancer immunological prevention

Figure 1

BALB-neuT mammary gland morphology and transcription profile similarities. A) Morphological preparation called "whole mount", that allows the observation of the entire mammary gland. The draining lymph node, vessels, ducts and ductules are evident. Clearly the amount of tumor mass increases from 6 to 22 weeks. 19 weeks picture was omitted since it is very similar to 22 weeks. At 26 weeks the tumor mass is palpable in all the mammary glands, and the "whole mount" picture is very similar to 22 weeks old mice (not shown). B) Euclidean distance of the expression profiles derived by mammary glands from 6 to 26 weeks old BALB-neuT mice measured with respect to 6 weeks old mice. Black dots refer to the average distance generated using all microarray data. Red dots refer to the average distance calculated using only microarray data showing an IQR greater than 0.5.

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