SIMAGE: si mulation of DNA-m icroa rray g ene e xpression data

BMC Bioinformatics

Table 1 Comparison of the properties of different DNA-microarray simulation models described in literature. '+' and '-' indicate availability of the indicated feature in the specified model. Note that the modeling of features in the specific models is usually not the same.

	Method	SIMAGE, this study	Lalush et al. [23]	Balagurunathan et al. [24]	Lonnstedt et al. [25]	Wierling et al. [26]	GE2
model implementation	tabulated gene expression data	+	-	-	-	-	+
	modeling of gene networks	-	-	-	-	-	+
	TIFF output	-	+	+	+	+	-
	software available	+ [5]	+ ¹	-	-	-	+ [27]
	adjustable model	+	+	+	+	-	+/-
model effects	background surface pattern	+	-	+	-	+	-
	spot pin / grid effects	+	+	+	-	-	-
	channel effects	+	-	+	-	-	-
	non-linearity effects	+	-	+	-	-	+
	missing data	+	-	+	-	-	-
	'fishtailing'	+	-	+	-	-	+
	spot shape / size	-	+	+	-	-	-

ISSN: 1471-2105