Figure 1

Example of a graph representing biological data and how it can be used to infer new information. The graph vertices are represented by boxes and are associated to biological entities (Organism, Chromosome, Gene etc). The edges (arrows) represent the relationships between these entities (Chromosome BelongsTo Organism, Gene IstranslatedTo Protein). On this example, genes holA and HP1247 are known to be orthologs (COG1466) but the protein product of HP1247 is not annotated in the sequence databank (RefSeq). The graph suggests to annotate the product of HP1247 as the delta subunit of polymerase III.