Figure 1

Experimental demonstration of bounded Sig. Sig(m₁) + Sig(m₂) is plotted against Sig(m₁ + m₂), where m₁ and m₂ differ by one mismatch. This assumption assures the existence of a degenerate consensus motif that precisely describes {m₁, m₂}. A. Simulation in which k, λ ∈ [0, 50] and t = ∞. Four variations were run, in which the parameters for m₁ and m₂ were identical (red □), had different k (blue +), had different λ (green *) or had different k and λ (magenta x). B. Known binding sites from SCPD that differ by one mismatch. t is the number of l-length substrings in the 800 bases upstream of the translation start sites of each gene in the regulon.