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Table 1 Summary of QC LMS controls. Theoretical fold-changes for the spike-in control probes in the QC LMS data set are shown. M values have been rounded to 2 decimal places.

From: Empirical array quality weights in the analysis of microarray data

Control (abbreviation)

Ratio R:G

M= log2(R/G)

Up-regulated 3-fold (U03)

3:1

log2 3 = 1.58

Up-regulated 10-fold (U10)

10:1

log2 10 = 3.32

Down-regulated 3-fold (D03)

1:3

-log2 3 = -1.58

Down-regulated 10-fold (D10)

1:10

-log2 10 = -3.32

Dynamic Range (DR)

1:1

log2 1 = 0.00