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Table 4 Assessment of the "Top 50 genes" page.

From: The Autoimmune Disease Database: a dynamically compiled literature-derived database

 

# Gene-Disease Associations in GAD

# correct Gene-Disease Associations not in GAD

# False Recognition

Precision of Gene Recognition

Examples False Recognition

RANK based method

35

9

6

88% (44/50)

IDDM2 (insulin dependent diabetes mellitus type II)

CD8A (CD8-Cells)

IgAN (IgA-Nephropathy)

ACR (Albumin-To-Creatinine-Ratio)

Frequency based method

34

11

5

90% (45/50)

IDDM2 (insulin dependent diabetes mellitus type II)

CD8A (CD8-Cells)

PLF (Pulmonary function)

  1. The top 50 genes from the AIDB were evaluated in comparison to GAD (# genes found in GAD, correct genes not found in GAD and falsely recognised genes). The resulting precision of gene recognition is 88% for the RANK based method and 90% for the frequency based method. Erroneously recognised genes are listed in the last column.
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BMC Bioinformatics

ISSN: 1471-2105

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