Example | Type of data used | PROMPT methoda: | Applied statistical methodsd |
---|---|---|---|
Fold comparison of GroEL substrates with the whole proteome | { Nominal }, { Nominal } | Categorical feature comparison b | • Chi-Square test |
Fold enrichment of GroEL substrates | { Nominal }, subset of { Nominal } | Categorical feature enrichment c | • Sampling from hypergeometric distribution with correction |
Abundance distribution of essential vs. all proteins | { Numeric }, { Numeric } | Numeric distribution comparison | • Mann-Whitney (MW) and Kolmogorov-Smirnov (KS) of the whole distribution • MW and Chi-Square test of each bin separately |
Protein abundance vs. mRNA expression | { Numeric × Numeric } | Numeric feature correlation | • Pearson correlation coefficient and • Pearson correlation test |