Table 1 Significant TFBS of QTC subclusters from the AML data set.
From: Analysis of promoter regions of co-expressed genes identified by microarray analysis
Clusters | Subclusters | Number of genes | Significant TFBS present in all promoters of a given cluster |
|---|---|---|---|
1 | 1A | 13 | Significant TFBS but not present in all |
1B | 16 | No significant | |
2 | 2A | 7 | AP1, CETS1P54, ETS1, HAND1E47, MYOD |
2B | 7 | No significant | |
2C | 14 | No significant | |
3 | 3A | 3 | AHR, AP1, AREB6, ATATA, BARBIE, CAAT, CDPCR3HD, CEBPDELTA, CETS168, CETS1P54, CHOP, CP2, E2F1, ELK1, ETS1, ETS2, FOXD3, FOXJ2, FOXO4, FREAC2, FREAC7, GATA, GATA1, GATA2, GATA3, GFI1, HAND1E47, HEB, HFH3, HFH8, HNF3ALPHA, HNF3B, HNF6, IK1, IPF1, LDSPOLYA, LHX3, LMO2COM, MAZ, MTATA, MYOD, NFY, NKX25, OCT1, PADS, POU1F1, RFX1, S8, SOX9, TAL1BETAE47, TATA, TCF1P, TGIF, TITF1, XFD1, XFD3, ZTA |
3B | 12 | No significant | |
3C | 6 | CAAT, CMYB, FOXO4 | |
41 | - | - | - |
5 | 5A | 6 | Significant TFBS but not present in all |
5B | 3 | No significant | |
5C | 10 | AP1, BARBIE, ER, GATA, GATA1, LMO2COM | |
6 | 6A | 8 | Significant TFBS but not present in all |
6B | 7 | Significant TFBS but not present in all | |
7 | 7A | 3 | FOXO4, MYOD |
7B | 6 | No significant | |
8 | 8A | 7 | BARBIE, CAAT, CEBPDELTA, ELK1, ETS1, ETS2, FOXJ2, FOXO4, FREAC7, GATA, GATA1, GATA3, GFI1, HFH3, HNF3ALPHA, HNF3B, LMO2COM, TGIF |
8B | 6 | No significant | |
9 | 9A | 7 | No significant |
9B | 5 | CETS168, IK1, MYOD, NRF2 | |
10 | 10A | 4 | Significant TFBS but not present in all |
10B | 5 | AP1, CETS1P54, ER, FOXO4, GATA1 | |
11 | 11A | 5 | No significant |
11B | 6 | GATA, IK1, MYOD | |
12 | 12A | 4 | GATA1, GATA2 |
12B | 7 | Significant TFBS but not present in all | |
13 | 13A | 3 | No significant |
13B | 5 | CETS168, CMYB, IK1, MYCMAX, NRF2, TFIII |