Table 2 Results for predicting potential effects of annotated amino acid substitutions occurring in human proteins and collected in the Swiss-Prot database.
From: Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
| Â | Support vector machine | Random forest | ||||
|---|---|---|---|---|---|---|
| Â | AUC | BER | MCC | AUC | BER | MCC |
Bao & Cui [20] | N/A | 0.318 | 0.274 | N/A | 0.292 | 0.315 |
Continuous form | 0.817 | 0.258 | 0.463 | 0.831 | 0.245 | 0.491 |
Discrete form | 0.806 | 0.259 | 0.457 | 0.817 | 0.262 | 0.451 |