Figure 14

Local trees for the CF dataset. Illustration of the decision trees and scores of markers (Prob-score) for the cystic fibrosis data set. In each circle diagram, the case leaves are red and the control leaves green. The branching patterns are defined by the markers included in the segment around the marker in focus, which is also placing the root in the decision tree. The decision trees shown are before pruning is attempted. Pruning collapses som of the branch points. The score is then calculated and can be seen to attain a maximum close the the true location of the the causative mutation (vertical line). The decision trees can also be visually seen to cluster cases more around the causative variant.