Figure 4

Comparison of the assignment where final electron acceptors are considered to the default assignment. The numbers of made direction assignments of the standard assignment procedure (A) and the assignment procedure, which additionally drew on the direction of electron transfer within the respiratory chain (B) are compared. The numbers (1 – 2c) refer to the assignment steps depicted in Fig. 1, while step 0 represents the reaction directions that were assigned by the additional heuristic rule based on final electron acceptors.