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Table 1 Relative effects of steady state perturbations on metabolite concentrations and rates. The metabolites and the rates are given relative to their reference states

From: A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kinetics

Perturbation Applied

 

eIN/eIN0 = 1.2

eATPase/eATPase0 = 0.9

eGAPD/eGAPD0 = 0.8

Normalized metabolites

Gext'

0.793

1

1

Gin'

1.128

0.999

1

G6P'

1.15

1.103

1

FdP'

1.093

0.959

1.369

PEP'

1.131

1.055

0.908

ATP'

1.045

1.071

1

Pol'

3.053

2.208

1

Gol'

1.077

0.983

1

EtOH'

1.077

0.983

1

Normalized rates

VIN'

1.104

1

1

VHK'

1.104

1

1

VPFK'

1.077

0.983

1

VGAPD'

1.077

0.983

1

VPK'

1.077

0.983

1

VPol'

3.053

2.208

1

VGol'

1.077

0.983

1

VATPase'

1.045

0.964

1