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Table 2 List of Ingenuity networks generated by mapping the focus genes that were differentially expressed between large and small colony mutants.

From: Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of L5178Y mouse lymphoma cells

Network

Genes*

Score#

Focus Genes

Top Functions

1

Add3, Adora3, Agt, Asf1b, Cdkn1b, Cdkn2a, Cks1b, Col6a1, Col6a2, Cspg2, Ctcf, Cyp11b2, Egfr, Eps8, Erbb2, Fbn1, Fgfr1, Gbp4, Gpc1, Hmga2, Il17rd, Irf4, Mell1, Nfatc2, Nfib, Nppa, Npr3, P4ha2, Ptrf, Rag2, Tgfbr2, Tlk2, Top1, Tp53inp1, Wap

25

15

Cellular Growth and Proliferation, Cancer, Cell Death

2

Acsl1, Angpt1, Btg1, Btg2, Ccnt1, Ccnt2, Cdk9, Cebpa, Chrm1, Dgkz, Efna1, Elf1, Epha7, Fbl, Grn, His1, Ifi203, Lamb2, Mapk1, Mmp17, Myc, Nme2, Oas1, Ptprc, Ptx3, Rasgrp1, Rn7sk, Rock1, Slpi, Spry4, Sytl1, Tapbp, Tdrd7, Tnf, Trib1

21

13

Gene Expression, Cellular Development, Cell-To-Cell Signaling and Interaction

3

Alox15, Btg1, Cdkn1a, Cks1b, Col6a1, Col6a2, Col6a3, Ctcf, Ebi3, Fgf13, Gata6, Gvin1, Ifi35, Ifi202b, Ifna, Ifne1, Ifng, Il15, Il12rb1, Il17f, Il27ra, Isgf3g, Mylk, Nd6, Ndufs4, Pdgfc, Pdgfra, S100a11, Sema3b, Sepp1, Stat1, Stat4, Tgfb1, Trim30, Znf467

19

12

Cancer, Cell Death, Cellular Growth and Proliferation

4

Casp3, Cckbr, Cd1d, Cdh2, Ctcf, Ctnna2, Ctnnb1, Ctnnd2, Cyp24a1, Edil3, Ets1, Gypa, Il2, Invs, Lmo2, Mdm4, Mgat5, Neu3, Nf2, Pag, Pitx2, Ppp2ca, Ppp2cb, Ppp2r2c, Ppp2r5b, Ptn, Ptp4a3, Ptprc, Scn5a, Slc4a1, Snrpd1, Sptbn1, Tbxas1, Tp53, Tuba1

19

12

Cellular Development, Hematological System Development and Function, Immune and Lymphatic System Development and Function

  1. Note: * Bold genes are those mapped by the significant genes. # A score of 3 or greater was considered significant (p < 0.001)
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BMC Bioinformatics

ISSN: 1471-2105

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