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Figure 4 | BMC Bioinformatics

Figure 4

From: Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation of Escherichia coli

Figure 4

Fermentation of formate was up-regulated processing pyruvate into formate via pyruvate lyase. Pyruvate is degraded to formic acid (formate), which then is either expelled (via transporters), or further degraded into H2 and CO2 by the formate hydrogenlyase complex (for more details see text). Reactions are symbolised by squares, metabolites by circles. Green (red) squares indicate significant up (down)-regulation (p-value ≤ 0.05) under anaerobic conditions.

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