From: Hinge Atlas: relating protein sequence to sites of structural flexibility
Category | Amino acids | Hinge Residues (count) | All residues (count) | Hinge Residues (expected) | HI | P-value |
---|---|---|---|---|---|---|
Aliphatic | I, L, V | 144 | 11915 | 190 | -0.120 | 5.9·10-05 |
Aromatic | H, F, W, Y | 82 | 5718 | 91 | -0.0454 | 0.14 |
 | A, C, G, H, I, L, K, |  |  |  |  |  |
Hydrophobic | M, F, T, W, Y, V | 521 | 35278 | 562 | -0.0326 | 0.0023 |
Negative | D, E | 102 | 6774 | 108 | -0.0242 | 0.29 |
Charged | R, D, E, H, Y | 212 | 13931 | 227 | -0.0196 | 0.24 |
Positive | R, H, Y | 110 | 7157 | 114 | -0.0153 | 0.37 |
 | R, N, D, E, Q, H, Y, |  |  |  |  |  |
Polar | S, T, W, Y | 488 | 29427 | 468 | 0.0178 | 0.096 |
 | A, N, D, C, G, P, S, |  |  |  |  |  |
Small | T, V | 502 | 28430 | 453 | 0.0450 | 0.00041 |
Tiny | G, A, S | 253 | 12247 | 195 | 0.113 | 0.0000023 |