Figure 4
From: Single TNFα trimers mediating NF-κ B activation: stochastic robustness of NF-κ B signaling
Single cell experiment and simulation. Panel A: Nuclear-to-cytoplasmic NF-κ B oscillations measured by Nelson et al. [33] shown for four SKNAS cells (marked by different colors) stimulated by 10 ng/ml TNFα. Panels B to F: IKKa and NF-κ B oscillation amplitude resulting from model simulations, respectively for TNFα dose: 10, 1, 0.3, 0.1 and 0.03 ng/ml. In each panel we show three single cell simulations, marked by different colors.