Table 6 Augmentation of differentially expressed genes in TIGR functional groups by addition of operon and monotonic analyses to CyberT analysis
| Â | CyberT | CyberT + operon + monotonic | ||
|---|---|---|---|---|
TIGR function* | No. genes | p-value | No. genes | p-value |
Protein and peptide secretion and trafficking | 6 | 0.013 | 21 | 1.86 × 10-9 |
Heme, porphyrin, and cobalamin biosynthesis | 1 | 0.335 | 15 | 4.83 × 10-7 |
Thiamine biosynthesis | 2 | 0.106 | 8 | 2.41 × 10-5 |
Transposon functions | 14 | 0 | 16 | 0.0001 |
Regulatory functions | 3 | 0.011 | 11 | 0.003 |
Unknown | 41 | 0.003 | 115 | 0.010 |
Cell division; Prophage functions | 2 | 0.002 | 2 | 0.011 |
Chemotaxis and motility | 3 | 0.170 | 9 | 0.016 |
Anions transport and binding | 4 | 0.013 | 6 | 0.018 |
Central intermediary metabolism | 4 | 0.199 | 16 | 0.022 |
Biosynthesis of murein sacculus and peptidoglycan | 1 | 0.266 | 1 | 0.033 |
DNA replication, recombination, and repair | 13 | 0.0003 | 15 | 0.040 |
Sulfur metabolism | 4 | 0.003 | 4 | 0.042 |
Amino acids and amines metabolism | 0 | NA | 1 | 0.044 |
Surface structures | 1 | 0.229 | 9 | 0.047 |
Transport and binding proteins | 0 | NA | 1 | 0.048 |