From: Application of amino acid occurrence for discriminating different folding types of globular proteins
 |  |  |  |  |  | Sensitivity | Precision | F1 | |||
---|---|---|---|---|---|---|---|---|---|---|---|
ID | Fold | Fold Description | Â | Number | Ratio | wo | w | wo | w | wo | w |
 |  | all-α |  |  |  |  |  |  |  |  |  |
1 | a.3 | Cytochrome C | Â | 25 | 2 | 24 | 48 | 50 | 27 | 32 | 35 |
2 | a.4 | DNA/RNA binding 3-helical bundle | Â | 103 | 6 | 73 | 49 | 43 | 51 | 54 | 50 |
3 | a.24 | Four helical up and down bundle | Â | 26 | 2 | 23 | 38 | 35 | 20 | 28 | 26 |
4 | a.39 | EF hand-like fold | Â | 25 | 2 | 40 | 44 | 45 | 26 | 43 | 33 |
5 | a.60 | SAMdomain-like | Â | 26 | 2 | 8 | 27 | 29 | 12 | 12 | 16 |
6 | a.118 | α-α superhelix |  | 47 | 3 | 47 | 45 | 50 | 50 | 48 | 47 |
 |  | all-β |  |  |  |  |  |  |  |  |  |
7 | b.1 | Immunoglobulin-like β-sandwich |  | 173 | 11 | 76 | 38 | 41 | 69 | 54 | 49 |
8 | b.2 | Common fold of diphtheria toxin/transcription factors/cytochrome f | Â | 28 | 2 | 4 | 29 | 11 | 21 | 5 | 24 |
9 | b.6 | Cupredoxin-like | Â | 30 | 2 | 27 | 37 | 42 | 22 | 33 | 27 |
10 | b.18 | Galactose-binding domain-like | Â | 25 | 2 | 20 | 36 | 50 | 26 | 29 | 30 |
11 | b.29 | Concanavalin A-like lectins/glucanases | Â | 26 | 2 | 23 | 27 | 24 | 18 | 24 | 22 |
12 | b.34 | SH3-like barrel | Â | 42 | 3 | 0 | 29 | 0 | 20 | - | 24 |
13 | b.40 | OB-fold | Â | 78 | 5 | 22 | 24 | 24 | 24 | 23 | 24 |
14 | b.82 | Double-stranded α-helix |  | 34 | 2 | 12 | 18 | 19 | 17 | 15 | 17 |
15 | b.121 | Nucleoplasmin-like | Â | 42 | 3 | 52 | 52 | 51 | 47 | 52 | 49 |
 |  | α/β |  |  |  |  |  |  |  |  |  |
16 | c.1 | TIM barrel | Â | 145 | 9 | 44 | 27 | 57 | 65 | 50 | 38 |
17 | c.2 | NAD(P)-binding Rossmann-fold domains | Â | 77 | 5 | 34 | 31 | 30 | 32 | 32 | 32 |
18 | c.3 | FAD/NAD(P)-binding domain | Â | 31 | 2 | 10 | 16 | 13 | 11 | 11 | 13 |
19 | c.23 | Flavodoxin-like | Â | 55 | 3 | 11 | 5 | 17 | 8 | 13 | 7 |
20 | c.26 | Adenine nucleotide a hydrolase-like | Â | 34 | 2 | 12 | 29 | 14 | 22 | 13 | 25 |
21 | c.37 | P-loop containing nucleoside triphosphate hydrolases | Â | 95 | 6 | 43 | 34 | 42 | 53 | 43 | 41 |
22 | c.47 | Thioredoxin fold | Â | 32 | 2 | 9 | 19 | 38 | 10 | 15 | 13 |
23 | c.55 | Ribonuclease H-like motif | Â | 49 | 3 | 4 | 6 | 11 | 8 | 6 | 7 |
24 | c.66 | S-adenosyl-L-methionine-dependent methyltransferases | Â | 34 | 2 | 29 | 29 | 31 | 21 | 30 | 24 |
25 | c.69 | α/β-Hydrolases |  | 37 | 2 | 35 | 41 | 39 | 34 | 37 | 37 |
 |  | α + β |  |  |  |  |  |  |  |  |  |
26 | d.15 | β-Grasp, ubiquitin-like |  | 42 | 3 | 5 | 21 | 40 | 18 | 9 | 19 |
27 | d.17 | Cystatin-like | Â | 25 | 2 | 0 | 8 | - | 4 | - | 5 |
28 | d.58 | Ferredoxin-like | Â | 118 | 7 | 32 | 7 | 17 | 25 | 22 | 11 |
 |  | small |  |  |  |  |  |  |  |  |  |
29 | g.3 | Knottins | Â | 80 | 5 | 98 | 89 | 72 | 82 | 83 | 85 |
30 | g.41 | Rubredoxin-like | Â | 28 | 2 | 11 | 71 | 75 | 32 | 19 | 44 |