Skip to main content

Table 1 Statistical/Functional data of determined modules.

From: Growing functional modules from a seed protein via integration of protein interaction and gene expression data

Functional Modules

Protein Complexes in Functional Modules

Seed Protein

Connectivity Density

Members

R

MIPS Protein Complex

p-Value

YGR210c

0.61

12

0.91

1. eIF2B*

2. eIF2*

3. Cytoplasmic translation init

<1e-14

5.4e-10

<1e-14

CDC39 (YCR093w)

0.73

20

0.75

1. NOT complex*

2. DNA polymerase alpha (I) – primase*

3. CCR4 complex

1.9e-13

7.5e-11

<1e-14

TAF5 (YBR198c)

0.79

30

0.83

1. TFIID*

2. TAFIIs*

3. SAGA*

4. ADA

<1e-14

<1e-14

<1e-14

<1e-14

RPB5 (YBR154c)

0.73

32

0.77

1. RNA polymerase III

2. RNA polymerase I

<1e-14

<1e-14

SRB6 (YBR253w)

0.77

26

0.89

1. RNA polymerase II holoenzyme

2. Kornberg's mediator (SRB)

3. Srb10p* complex

<1e-14

<1e-14

2.3e-10

PRE3 (YJL001w)

0.83

18

0.81

1. 20S proteasome*

2. 26S proteasome

<1e-14

<1e-14

SEC10 (YLR166c)

0.75

10

0.80

1. Exocyst complex

<1e-14

RFC5 (YBR087w)

0.84

10

0.92

1. Replication factor C complex*

<1e-14

ARC18 (YLR370c)

0.77

6

0.87

1. Arp2p/Arp3p complex

<1e-14

SEC27 (YGL137w)

0.97

10

1.0

1. TRAPP

<1e-14

  1. The sub-columns of 'Functional Modules' contain statistical data for various modules of different size, while in the two last sub-columns we display the MIPS description of the basic complexes of each module and their corresponding p-values. (*) DMSP manages to find the entire complex.