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Table 1 The major relevant functions altered by riddelliine treatment in liver

From: Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats

Function Category

Significance

Associated Genes

Tissue Development

2.59E-5 – 4.05E-2

64

Cell Morphology

3.35E-5 – 3.99E-2

64

Cancer

8.84E-5 – 3.99E-2

70

Cell Death

8.84E-5 – 3.99E-2

66

Cell-To-Cell Signaling and Interaction

5.51E-4 – 4.05E-2

58

Lipid Metabolism

7.31E-4 – 3.99E-2

44

Cellular Development

2.12E-3 – 3.56E-2

58

Cellular Growth and Proliferation

2.12E-3 – 3.99E-2

37

Cell Cycle

3.96E-3 – 4.04E-2

31

Cellular Movement

4.00E-3 – 3.89E-2

39