Figure 1
From: Information transfer in signaling pathways: A study using coupled simulated and experimental data
Different calcium dynamics and coupled enzyme. Coupling of the stochastically simulated activation of an enzyme to simulated calcium time series with different dynamical behavior according to Eq. (1). From top left to bottom right we see a spiking (A), bursting (B), irregular (C) behavior and overstimulation (D). k2 values 2, 2.85, 2.99 and 3.2, respectively, and volume 10-12 [arbitrary units]. x-axis: time [s]. y-axis: concentration of Ca2+ and the active form of the enzyme Pact and the enzyme's K M value.