Clustering of cognate proteins among distinct proteomes derived from multiple links to a single seed sequence

BMC Bioinformatics

Table 1 Comparison of Seed Linkage versus MultiParanoid using manually curated clusters as a reference.

	Seed Linkage	MultiParanoid
Number of RCs	263	214
Additional sequences	275 (153^a)	224
Singlets (non clustered manual sequences)	38	179
RC = MC (perfect match)	13	132
RC = MC + additional sequences	118 (100^a)	28
RC = MC - some manual sequences^b	59	17
MC is split in two or more RC^b	15	9
Two or more MC are merged in RC^b	15	9

^aadditional sequences display two or more TM segments; ^bincluding or not additional sequences, MC: manually curated clusters, RC: rebuilt clusters.

ISSN: 1471-2105