Conserved co-expression for candidate disease gene prioritization

BMC Bioinformatics

Table 1 Pairwise species comparisons for co-expression-based disease gene ranking.

Individual species	# Disease gene pairs	Median rank	Pairwise combined sets	# Disease gene pairs	Median rank	P-value (Combined better than single species)
Human	3286	0.64	Human-Mouse	3114	0.67	6.7 × 10^-4 *
Mouse	3188	0.63				1.3 × 10^-5 *
Human	3286	0.64	Human-Fly	3176	0.66	0.007 *
Fly	3534	0.62				1.8 × 10^-5 *
Human	3286	0.64	Human-Worm	2954	0.67	2.1 × 10^-4 *
Worm	3264	0.63				9.1 × 10^-6 *
Human	3286	0.64	Human-Yeast	550	0.67	0.12
Yeast	674	0.69				0.74

ISSN: 1471-2105