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Table 1 Mammalian mRNAs that Utilize Alternative Initiation Sites (non-AUG) for Protein Translation

From: Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites

Accession

Protein Name

Codon

Species

Location

Ref.

NM_002110

hemopoietic cell kinase (hck)

CUG

Homo sapiens

172

[3]

NM_010407

hemopoietic cell kinase (hck) phosphoribosyl pyrophosphate synthetase 1-like 1

CUG

Mus musculus

186

[3]

NM_175886

(PRPS1L1)

ACG

Homo sapiens

82

[7]

NM_008523

leukocyte tyrosine kinase (ltk), tv 1

CUG

Mus musculus

228

[8]

NM_206941

leukocyte tyrosine kinase (ltk), tv 2

CUG

Mus musculus

228

[8]

NM_002467

v-myc myelocytomatosis viral oncogene homolog (Myc)

CUG

Homo sapiens

525

[9]

NM_012603

myelocytomatosis viral oncogene homolog (Myc)

CUG

Rattus norvegicus

537

[9]

NM_013185

hemopoietic cell kinase (hck)

CUG

Rattus norvegicus

116

[3]

NM_003674

cyclin-dependent kinase 10 (CDK10), tv 1

CUG

Homo sapiens

237

[10]

NM_003674

cyclin-dependent kinase 10 (CDK10), tv 1

CUG

Homo sapiens

255

[10]

NM_052987

cyclin-dependent kinase 10 (CDK10), tv 2

CUG

Homo sapiens

91

[10]

NM_052987

cyclin-dependent kinase 10 (CDK10), tv 2

GUG

Homo sapiens

109

[10]

NM_194444

cyclin-dependent kinase 10 (CDK10), tv 2

CUG

Mus musculus

91

[10]

NM_012890

solute carrier family 30 (zinc), member 2 (Slc30a2)

CUG

Rattus norvegicus

52

[11]

NM_000378

Wilms tumor 1 (WT1), tv A

CUG

Homo sapiens

197

[4]

NM_003213

TEA domain family member 4 (TEAD4), tv 1

UUG

Homo sapiens

275

[12]

NM_013507

p97, repressor translation

GUG

Mus musculus

333

[13]

NM_014293

neuronal pentraxin receptor (NPR)

CUG

Homo sapiens

155

[14]

NM_030689

neuronal pentraxin receptor (NPR)

CUG

Mus musculus

126

[14]

NM_030841

neuronal pentraxin receptor (NPR)

CUG

Rattus norvegicus

115

[14]

NM_009736

Bcl2-associated athanogene 1 (BAG1)

CUG

Mus musculus

34

[15]

NM_004323

BCL2-associated athanogene (BAG1)

CUG

Homo sapiens

73

[16]

NM_003889

Human nuclear receptor (hPAR)

CUG

Homo sapiens

1840

[17]

NM_002006

fibroblast growth factor 2 (FGF2)

CUG

Homo sapiens

303

[18]

NM_002006

fibroblast growth factor 2 (FGF2)

CUG

Homo sapiens

330

[18]

NM_002006

fibroblast growth factor 2 (FGF2)

CUG

Homo sapiens

345

[18]

NM_002006

fibroblast growth factor 2 (FGF2)

CUG

Homo sapiens

69

[18]

NM_021182

minor histocompatability antigen HB-1

CUG

Homo sapiens

108

[19]

NM_130385

tumor suppression (MRVI1)

CUG

Homo sapiens

502

[20]

NM_194464

tumor suppression (MRVI1)

CUG

Mus musculus

647

[20]

NM_003214

TREF-5 transcription enhancer factor

AUA

Homo sapiens

161

[21]

NM_199072

Human I-mfa domain-containing protein (HIC)

GUG

Homo sapiens

264

[22]

NM_031895

calcium channel, voltage-dependent (CACNG8)

CUG

Homo sapiens

104

[23]

NM_023064

spatial stromal protein associated thymii and lymph node

CUG

Mus musculus

84

[24]

NM_020860

stromal interaction molecule 2 (STIM2)

UUG

Homo sapiens

531

[25]

NM_133231

regulatory factor X-associated protein (RFXAP)

ACG

Mus musculus

97

[26]

NM_006386

DEAD box protein (DDX17)

CUG

Homo sapiens

75

[27]

NM_010592

Leucine zipper DNA binding protein (JUND1)

CUG

Mus musculus

139

[28]

NM_138875

Leucine zipper DNA binding protein (JUND1)

CUG

Rattus norvegicus

294

[28]

NM_001025366

vascular endothelial growth factor (VEGF), tv 1

CUG

Homo sapiens

492

[1]

NM_001025367

vascular endothelial growth factor (VEGF), tv 3

CUG

Homo sapiens

666

[1]

NM_001025368

vascular endothelial growth factor (VEGF), tv 4

CUG

Homo sapiens

908

[1]

NM_003376

vascular endothelial growth factor (VEGF), tv 2

CUG

Homo sapiens

645

[1]

NM_001017371

Sp3 transcription factor (SP3), tv 2

AUA

Homo sapiens

385

[29]

NM_001038634

DNase X (LOC515176)

CUG

Bos taurus

185

[30]

  1. This positive set of 45 validated RefSeq mammalian sequences have been identified as containing at least one alternative initiation site. This information was obtained from Genbank records and includes accession, protein name, annotated start codon, species and the relative start position. References for each alternative start site are provided (last column).