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Table 3 Significant functional gene sets related to p53 mutational status by Sub-GSE.

From: Testing gene set enrichment for subset of genes: Sub-GSE

Set Name

q-value

Hypoxia and p53 in the Cardiovascular system

<0.001

G1 and S Phases of the Cell Cycle

<0.001

p53 Signaling Pathway (p53 Pathway)

0.022

TrkA Signaling Pathway

0.022

P53 Upregulated Genes

0.022

p53 Signaling Pathway Genes(p53_signalling)

0.029

Cell Cycle: G2/M Checkpoint

0.029

G2 and M Phases of the Cell Cycle

0.029

Programmed Cell Death

0.029

DNA Damage Signaling Pathway

0.029

Radiation Sensitivity Genes

0.029

Cell Cycle Regulator Genes

0.029

ATM Signaling Pathway

0.029

Ceramide Signaling Pathway

0.029

Drug Resistance and Metabolism Genes

0.029

Stress Induction of HSP Regulation

0.029

Multi-step Regulation of Transcription by Pitx2

0.029

Fas Signaling Pathway

0.029

  1. Significant functional gene sets (q-value ≤ 0.03) detected in 50 of the NCI-60 cell lines. The q-values are calculated by Sub-GSE.