Figure 2

Visualization. A. Genes from the DNA microarray data were clustered. The size of each cluster is displayed in blue underneath the cluster name. Numbers in each colored rectangle represent absolute values of occurrences. The significance of the overrepresentation is visualized in a colour gradient which is displayed at the bottom of the plot. The description of each category is placed at the right. Multiple testing correction results are visualized using five different symbols to distinguish between the individual corrections. The number of symbols placed in each rectangle corresponds to the number of multiple testing corrections after which the annotation is found significant (see [13] for more details concerning this visualization). The graphical representation of the overrepresented DNA binding sites from the SCOPE algorithm consists of several components. The results of SCOPE based on a single cluster are discussed: B. The expression graph of the genes in the cluster. C. Contains information concerning overrepresented functional categories and a link to the results of DISCLOSE. D. Link to the results of SCOPE. E. The highest scoring motif found in the cluster. F. The highest scoring motif is compared with existing binding site information. The known motif that matches the putative motif best is displayed.