Figure 5

Kringle tip contacts with αvβ3 in the closed conformation. The α and β chains of αvβ3 are shown as pale pink and yellow spheres respectively. The stretch of amino acids homologous to the α325 peptide are in magenta, homology to β1P1 in orange, homology to β1P2 in yellow. Res 113-123 are shown as cartoons, those corresponding to the eighth ranking solution are in red, those corresponding to the ninth ranking solution are in green, those corresponding to the twelfth ranking solution are in blue.