Figure 6From: Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical simulationBlood Concentration/time profile of irinotecan, SN-38, APC, NPC, and SN-38 in blood compartment for solo administration of irinotecan. The drug concentrations in blood without ketoconazole administration was estimated by numerical simulation. Intravenous drip infusion (125 mg/m2, 90 min) was assumed for irinotecan administration.Back to article page