Figure 1From: Quantitative analysis of differences in copy numbers using read depth obtained from PCR-enriched samples and controls Dispersion correction. Illustration of the dispersion correction effect by Ï•. First row: before correction, second row: after correction. Calls for the sequencing data sets (M62 and M63) and both control samples (NA12898, NA19129) are plotted separately (in columns). A CNV is called if the determined Q score is higher than the threshold (normalized to 1 in this diagram). False classifications (FN: false negative, FP: false positive) are shown in red. Loci with known CNVs in the sample are shown as dots and loci with normal copy number are plotted as crosses.Back to article page