Figure 2

Gene-set p-values for KEGG pathways and Δ _k coefficients. The clustering heatmap shows gene set p-values depicted by color, with data set indicated in the row annotation track. Clustering was achieved by applying a Euclidean metric to – log₁₀ p-values and using Ward’s linkage method. Note that the gene set tests were conducted as exact Mantel-Haenzel tests, stratified by CpG Island status (27K) and by Infinium biochemistry type, relation to CpG Island, and gene region (450K).