Figure 1
From: Optimally choosing PWM motif databases and sequence scanning approaches based on ChIP-seq data
Comparison of performance of the dedicated commercial and public scanners. Shown are the average specificity and sensitivity +/−SD, for each tested database/scanner. MatIspector (A, C) or Match (B, D) were each separately compared to both matrix-scan and Bio.Motif; with either 3-rd exons (A, B) or flanks of the ChIP-seq peaks (C, D) used as the negative datasets. The color encodes scanners: matrix-scan (red), Bio.Motif (magenta), Match (green), MatInspector (blue). Stright lines through the points of average performance are the lines of equal balanced accuracy. Gray ovals in A, D mark the performance obtained with Genomatix motif families.