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Table 2 Conserved motifs of the GmrSD proteins

From: Phylogenomics and sequence-structure-function relationships in the GmrSD family of Type IV restriction enzymes

Domain

Described motif

Homologous motif of known function (protein)

Predicted function

GmrS

QR

Conserved residues present in the DGQHR domain, unknown function

No function prediction

GmrS

I/VDGQQR

FG/SGCHR – signature sequence of sulfiredoxins

NTP binding, endonuclease

GmrS

FxxxN

Conserved residues present in the DGQHR domain, unknown function

No function prediction

GmrD

E/D-H-N-N

D-H-N-N in HNH endonuclease from G. metallireducens, E-H-N-N in the periplasmic nuclease Vvn

Endonuclease