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Fig. 1 | BMC Bioinformatics

Fig. 1

From: The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes

Fig. 1

Performance across VERA FNA data set (n = 88) and genetic alterations observed by cytology (a) and histology subtype (b). The width of each band of the circos plots is proportional to the number of samples harboring a particular variant or fusion. A complete list of all variants and fusions detected can be found in Additional files 3 and 7. Abbreviations: AUS/FLUS atypia of undetermined significance/follicular lesion of undetermined significance, BFN benign follicular nodule, Cyto B cytology benign, Cyto M cytology malignant, FA follicular adenoma, FC follicular carcinoma, FN/SFN follicular neoplasm or suspicious for neoplasm, FVPTC follicular variant of papillary carcinoma, HCA Hurthle cell adenoma, HCC Hurthle cell carcinoma, LCT lymphocytic thyroiditis, MTC medullary thyroid carcinoma, NHP nodular hyperplasia, PTC papillary thyroid carcinoma, PTC-TCV papillary thyroid carcinoma-tall cell variant, SFM suspicious for malignancy, WDC-NOS well-differentiated carcinoma-not otherwise specified

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