Fig. 1

Illustration of mutational data. a Provides an overview of the global mutational profile of TP53, TSHZ3 and VHL highlighting the cancer entity specific occurrence of mutations within BRCA and KIRC, while TSHZ3, as control, remains undetected. In b and c, the mutational profile is broken down into the type of predicted impact on the protein sequences. The slice size denotes the proportion of a mutation type in relation to all mutations. The given percentage denotes the proportion of a mutation type in relation to all tumor samples of a given entity